For the Yomiuri Giants, in the big moment, nobody comes up bigger than "Big Daddy."

Alex Ramirez put the final nail in the coffin of the Hanshin Tigers' reign atop the Central League, for the moment at least, with a towering home run to center to help the Yomiuri Giants take sole possession of the CL lead with a 3-1 win in front of 46,783 fans on Wednesday night at Tokyo Dome.

Lee Seung Yeop drove in a pair of runs in the third to give the Giants a two-run advantage before the Tigers cut the lead in half in the sixth. With things getting tense, Ramirez highlighted a 3-for-4 day with his 43rd homer of the season in the seventh.