Pope Francis on Friday accused both Donald Trump and Kamala Harris of being "against life" as he returned to Rome from an epic 12-day tour of the Asia-Pacific.

The 87-year-old pontiff's comments on the U.S. presidential hopefuls came as he defied health concerns to connect with believers from the jungle of Papua New Guinea to the skyscrapers of Singapore.

It was Francis' longest trip in duration and distance since becoming head of the world's nearly 1.4 billion Roman Catholics more than 11 years ago.