President Donald Trump's nominee, Brett Kavanaugh, looked headed for a lifetime job on the U.S. Supreme Court on Friday after two crucial senators said that sexual misconduct accusations against the judge would not prevent them from voting to confirm him.

If Kavanaugh is approved in a final Senate vote, likely on Saturday, Trump will have achieved a victory in his drive to consolidate conservative dominance of the nation's highest court and move the American judiciary rightward.

Two key senators, Republican Susan Collins and Democrat Joe Manchin, both seen as swing votes, said they would support Kavanaugh, after weeks of debate about sexual violence and the nominee's character and temperament that gripped the nation.