LONDON –

What is the universe made of?

Astronomers face an embarrassing conundrum: they don't know what 95 percent of the universe is made of. Atoms, which form everything we see around us, only account for a measly 5 percent. Over the past 80 years it has become clear that the substantial remainder is comprised of two shadowy entities — dark matter and dark energy. The former, first discovered in 1933, acts as an invisible glue, binding galaxies and galaxy clusters together. Unveiled in 1998, the latter is pushing the universe's expansion to ever greater speeds. Astronomers are closing in on the true identities of these unseen interlopers.

Four billion years ago, something started stirring in the primordial soup. A few simple chemicals got together and made biology — the first molecules capable of replicating themselves appeared. We humans are linked by evolution to those early biological molecules. But how did the basic chemicals present on early Earth spontaneously arrange themselves into something resembling life? How did we get DNA? What did the first cells look like? More than half a century after the chemist Stanley Miller proposed his "primordial soup" theory, we still can't agree about what happened. Some say life began in hot pools near volcanoes, others that it was kick-started by meteorites hitting the sea.

Perhaps not. Astronomers have been scouring the universe for places where water worlds might have given rise to life, from Europa and Mars in our solar system to planets many light years away. Radio telescopes have been eavesdropping on the heavens and in 1977 a signal bearing the potential hallmarks of an alien message was heard. Astronomers are now able to scan the atmospheres of alien worlds for oxygen and water. The next few decades will be an exciting time to be an alien hunter with up to 60 billion potentially habitable planets in our Milky Way alone.