The farm ministry said Thursday that all cows nationwide that have been fed meat-and-bone meal and other suspected sources of mad cow disease will be disposed of, after the nation's second case of the brain-wasting illness was confirmed Wednesday in Hokkaido, ministry officials said.

Some 5,100 such cows in 15 prefectures will be incinerated after being screened, they said.

Other than meat-and-bone meal, suspected sources of infection include feed containing ingredients made of slaughtered animals's blood or bones.